|Other Names||Feline leukemia virus subgroup C receptor-related protein 2, Calcium-chelate transporter, CCT, FLVCR2, C14orf58|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as an importer of heme. Also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in non-hematopoietic tissues, with relative abundant expression in brain, placenta, lung, liver and kidney. Also expressed in hematopoietic tissues (fetal liver, spleen, lymph node, thymus, leukocytes and bone marrow). Found in acidophil cells of the pituitary that secrete growth hormone and prolactin|
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Provided below are standard protocols that you may find useful for product applications.
The FLVCR2 gene encodes a transmembrane protein that belongs to the major facilitator superfamily of secondary carriers that transport small solutes in response to chemiosmotic ion gradients, such as calcium.
Meyer, E., et al. Am. J. Hum. Genet. 86(3):471-478(2010)Brown, J.K., et al. J. Virol. 80(4):1742-1751(2006)Brasier, G., et al. Exp. Cell Res. 293(1):31-42(2004)Heilig, R., et al. Nature 421(6923):601-607(2003)
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