|Other Names||Guanine nucleotide-binding protein subunit beta-5, Gbeta5, Transducin beta chain 5, GNB5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.|
|Tissue Location||Expressed in multiple tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.
# Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)# Howlett, A.C., et al. J. Biol. Chem. 284(24):16386-16399(2009)# Rao, A., et al. J. Neurosci. 27(51):14199-14204(2007)# Drenan, R.M., et al. J. Biol. Chem. 281(38):28222-28231(2006)# Stelzl, U., et al. Cell 122(6):957-968(2005)
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