|Other Names||Carbonic anhydrase 5A, mitochondrial, Carbonate dehydratase VA, Carbonic anhydrase VA, CA-VA, CA5A, CA5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Reversible hydration of carbon dioxide. Low activity.|
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Provided below are standard protocols that you may find useful for product applications.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis.
Vullo, D., et al. Bioorg. Med. Chem. Lett. 17(5):1336-1340(2007)Saarnio, J., et al. J. Histochem. Cytochem. 47(4):517-524(1999)Parkkila, A.K., et al. J. Biol. Chem. 273(38):24620-24623(1998)
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