|Other Names||Carbonic anhydrase-related protein, CARP, Carbonic anhydrase VIII, CA-VIII, CA8, CALS|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Does not have a carbonic anhydrase catalytic activity.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
Picaud, S.S., et al. Proteins 76(2):507-511(2009)Turkmen, S., et al. PLoS Genet. 5 (5), E1000487 (2009) Mori, S., et al. J. Bone Miner. Metab. 27(2):213-216(2009)Nishikata, M., et al. Mol. Carcinog. 46(3):208-214(2007)
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