NEU1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P01178 |
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Gene ID | 5020 |
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Other Names | Oxytocin-neurophysin 1, OT-NPI, Oxytocin, Ocytocin, Neurophysin 1, OXT, OT |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | OXT |
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Synonyms | OT |
Function | Neurophysin 1 specifically binds oxytocin. |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
References
Rao, V.V., et al. Cytogenet. Cell Genet. 61(4):271-273(1992)Ivell, R., et al. Endocrinology 127(6):2990-2996(1990)Wood, S.P., et al. Science 232(4750):633-636(1986)Sausville, E., et al. J. Biol. Chem. 260(18):10236-10241(1985)
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