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TRPM3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9HCF6 |
|---|
| Gene ID | 80036 |
|---|---|
| Other Names | Transient receptor potential cation channel subfamily M member 3, Long transient receptor potential channel 3, LTrpC-3, LTrpC3, Melastatin-2, MLSN2, TRPM3, KIAA1616, LTRPC3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TRPM3 |
|---|---|
| Synonyms | KIAA1616, LTRPC3 |
| Function | Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation. In addition, forms heteromultimeric ion channels with TRPM1 which are permeable for calcium and zinc ions (PubMed:21278253). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
| Tissue Location | Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and spinal cord. Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down- regulated in renal tumors compared to normal kidney. Expressed in the lens (PubMed:25090642). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation.
References
Nagase T., et.al., DNA Res. 7:273-281(2000).Lee N., Chen J., et.al., J. Biol. Chem. 278:20890-20897(2003).
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