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HES7 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BYE0 |
|---|
| Gene ID | 84667 |
|---|---|
| Other Names | Transcription factor HES-7, hHes7, Class B basic helix-loop-helix protein 37, bHLHb37, Hairy and enhancer of split 7, bHLH factor Hes7, HES7, BHLHB37 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | HES7 |
|---|---|
| Synonyms | BHLHB37 |
| Function | Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
HES7 is a member of the hairy and enhancer of split family of bHLH transcription factors. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton.
References
Sparrow, D.B., et al. Hum. Mol. Genet. 17(23):3761-3766(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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