CPOX Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P36551 |
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Gene ID | 1371 |
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Other Names | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial, COX, Coprogen oxidase, Coproporphyrinogenase, CPOX, CPO, CPX |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CPOX (HGNC:2321) |
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Synonyms | CPO, CPX |
Function | Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX and participates to the sixth step in the heme biosynthetic pathway. |
Cellular Location | Mitochondrion intermembrane space. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CPOX is the sixth enzyme of the heme biosynthetic pathway. This enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme.
References
Li, T., et al. Toxicol. Sci. 109(2):228-236(2009)Aurizi, C., et al. Cell. Mol. Biol. (Noisy-le-grand) 55(1):15-18(2009)Gorman, C.S., et al. Ir Med J 101 (4), 125 (2008)
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