|Other Names||Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial, COX, Coprogen oxidase, Coproporphyrinogenase, CPOX, CPO, CPX|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.|
|Cellular Location||Mitochondrion intermembrane space.|
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Provided below are standard protocols that you may find useful for product applications.
CPOX is the sixth enzyme of the heme biosynthetic pathway. This enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme.
Li, T., et al. Toxicol. Sci. 109(2):228-236(2009)Aurizi, C., et al. Cell. Mol. Biol. (Noisy-le-grand) 55(1):15-18(2009)Gorman, C.S., et al. Ir Med J 101 (4), 125 (2008)
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