|Other Names||Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma, Protein phosphatase subunit G5PR, Rhabdomyosarcoma antigen MU-RMS-406A/6C, PPP2R3C, C14orf10, G5PR|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.|
|Cellular Location||Nucleus. Cytoplasm. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis.|
|Tissue Location||Ubiquitously expressed in brain and other tissues.|
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Provided below are standard protocols that you may find useful for product applications.
P2R3C may regulate MCM3AP phosphorylation through phosphatase recruitment. It may play a role in the activation-induced cell death of B-cells (By similarity).
Xing, Y., et al. J. Exp. Med. 202(5):707-719(2005)Kamnasaran, D., et al. Genomics 85(5):608-621(2005)Kono, Y., et al. Genes Cells 7(8):821-834(2002)
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