P2R3C Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q969Q6 |
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Gene ID | 55012 |
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Other Names | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma, Protein phosphatase subunit G5PR, Rhabdomyosarcoma antigen MU-RMS-406A/6C, PPP2R3C, C14orf10, G5PR |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PPP2R3C |
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Synonyms | C14orf10, G5PR |
Function | May regulate MCM3AP phosphorylation through phosphatase recruitment (By similarity). May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex (PubMed:24333728). May play a role in the activation-induced cell death of B-cells (By similarity). |
Cellular Location | Nucleus. Cytoplasm. Note=Excluded from the nucleoli Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis. |
Tissue Location | Ubiquitously expressed in brain and other tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
P2R3C may regulate MCM3AP phosphorylation through phosphatase recruitment. It may play a role in the activation-induced cell death of B-cells (By similarity).
References
Xing, Y., et al. J. Exp. Med. 202(5):707-719(2005)Kamnasaran, D., et al. Genomics 85(5):608-621(2005)Kono, Y., et al. Genes Cells 7(8):821-834(2002)
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