|Other Names||Transmembrane 4 L6 family member 4, Intestine and liver tetraspan membrane protein, IL-TMP, TM4SF4, ILTMP|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Jejunum and liver.|
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Provided below are standard protocols that you may find useful for product applications.
T4S4 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation. The use of alternate polyadenylation sites has been found for this gene.
Qiao, J., et al. Reprod. Biomed. Online 17(3):425-435(2008)Berditchevski, F. J. Cell. Sci. 114 (PT 23), 4143-4151 (2001) Wright, M.D., et al. Protein Sci. 9(8):1594-1600(2000)
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