MTIF3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H2K0 |
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Gene ID | 219402 |
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Other Names | Translation initiation factor IF-3, mitochondrial, IF-3(Mt), IF-3Mt, IF3(mt), IF3mt, MTIF3 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MTIF3 |
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Function | IF-3 binds to the 28S ribosomal subunit and shifts the equilibrium between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. |
Cellular Location | Mitochondrion. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease.
References
Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)Christian, B.E., et al. Biochemistry 48(15):3269-3278(2009)Thorleifsson, G., et al. Nat. Genet. 41(1):18-24(2009)Sullivan, P.F., et al. Mol. Psychiatry 13(6):570-584(2008)Haque, M.E., et al. Nucleic Acids Res. 36(2):589-597(2008)Abahuni, N., et al. Neurosci. Lett. 414(2):126-129(2007)
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