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NCR3 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O14931
Peptide ID 90625130
Additional Information
Gene ID 259197
Other Names Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NKp30, CD337, NCR3, 1C7, LY117
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NCR3
Synonyms 1C7, LY117
Function Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Selectively expressed by all resting and activated NK cells and weakly expressed in spleen {ECO:0000269|PubMed:10562324, ECO:0000269|Ref.2}
Research Areas
Citations (0)

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Natural cytotoxicity receptors (NCRs), such as NCR3, are activating natural killer (NK) cell receptors that belong to the immunoglobulin (Ig) superfamily. NCR3 is expressed in all resting and activated NK cells and forms a complex with CD3-zeta.


Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) Balsamo, M., et al. Exp. Hematol. 37(10):1167-1175(2009)Hoechst, B., et al. Hepatology 50(3):799-807(2009)Brandt, C.S., et al. J. Exp. Med. 206(7):1495-1503(2009)Djeu, J.Y., et al. Clin. Cancer Res. 8(3):636-640(2002)Sato, M., et al. Tissue Antigens 58(4):255-258(2001)Sivakamasundari, R., et al. Immunogenetics 51 (8-9), 723-732 (2000)

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$ 80.00
Cat# BP9767c
Availability: In Stock
Bulk Size
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