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SUPV3L1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8IYB8
Peptide ID 90625226
Additional Information
Gene ID 6832
Other Names ATP-dependent RNA helicase SUPV3L1, mitochondrial, Suppressor of var1 3-like protein 1, SUV3-like protein 1, SUPV3L1, SUV3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SUPV3L1
Synonyms SUV3
Function Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Cellular Location Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid
Tissue Location Broadly expressed.
Research Areas
Citations (0)

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SUV3L1 is an ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction. It may protect cells from apoptosis.


Szczesny, R.J., et al. Nucleic Acids Res. 38(1):279-298(2010)Wang, D.D., et al. J. Biol. Chem. 284(31):20812-20821(2009)Khidr, L., et al. J. Biol. Chem. 283(40):27064-27073(2008)Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008)Pereira, M., et al. Mech. Ageing Dev. 128 (11-12), 609-617 (2007) Shu, Z., et al. Biochemistry 43(16):4781-4790(2004)

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$ 80.00
Cat# BP9772a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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