ZNF202 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95125 |
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Gene ID | 7753 |
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Other Names | Zinc finger protein 202, Zinc finger protein with KRAB and SCAN domains 10, ZNF202, ZKSCAN10 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ZNF202 |
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Synonyms | ZKSCAN10 |
Function | Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease. |
Cellular Location | Nucleus. |
Tissue Location | Highly expressed in testis. Also expressed in breast carcinoma cell lines |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF202 (Zinc finger protein 202) is a transcriptional repressor of genes affecting the vascular endothelium as well as lipid metabolism and energy homeostasis. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease.
References
Aberg, K., et al. Biol. Psychiatry 67(3):279-282(2010)Drenos, F., et al. Hum. Mol. Genet. 18(12):2305-2316(2009)Patterson, E.S., et al. Physiol. Genomics 34(3):277-284(2008)Stene, M.C., et al. J. Am. Coll. Cardiol. 52(5):369-377(2008)Stene, M.C., et al. J. Lipid Res. 47(5):944-952(2006)
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