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ZNF202 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O95125
Peptide ID 90625269
Additional Information
Gene ID 7753
Other Names Zinc finger protein 202, Zinc finger protein with KRAB and SCAN domains 10, ZNF202, ZKSCAN10
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF202
Synonyms ZKSCAN10
Function Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease.
Cellular Location Nucleus.
Tissue Location Highly expressed in testis. Also expressed in breast carcinoma cell lines
Research Areas
Citations (0)

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Background

ZNF202 (Zinc finger protein 202) is a transcriptional repressor of genes affecting the vascular endothelium as well as lipid metabolism and energy homeostasis. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease.

References

Aberg, K., et al. Biol. Psychiatry 67(3):279-282(2010)Drenos, F., et al. Hum. Mol. Genet. 18(12):2305-2316(2009)Patterson, E.S., et al. Physiol. Genomics 34(3):277-284(2008)Stene, M.C., et al. J. Am. Coll. Cardiol. 52(5):369-377(2008)Stene, M.C., et al. J. Lipid Res. 47(5):944-952(2006)

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$ 80.00
Cat# BP9774c
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