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GRPR Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P30550
Peptide ID 91013078
Additional Information
Gene ID 2925
Other Names Gastrin-releasing peptide receptor, GRP-R, GRP-preferring bombesin receptor, GRPR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain
Research Areas
Citations (0)

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Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.


Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)Chao, C., et al. J. Surg. Res. 156(1):26-31(2009)Ananias, H.J., et al. Prostate 69(10):1101-1108(2009)Fleischmann, A., et al. Endocr. Relat. Cancer 16(2):623-633(2009)

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$ 80.00
Cat# BP9790c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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