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EHBP1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NDI1 |
|---|
| Gene ID | 23301 |
|---|---|
| Other Names | EH domain-binding protein 1, EHBP1, KIAA0903, NACSIN |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | EHBP1 |
|---|---|
| Synonyms | KIAA0903, NACSIN |
| Function | May play a role in actin reorganization. Links clathrin- mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle trafficking (PubMed:14676205, PubMed:27552051). Required for perinuclear sorting and insulin- regulated recycling of SLC2A4/GLUT4 in adipocytes (By similarity). |
| Cellular Location | Cytoplasm. Membrane. Endosome Note=Mostly found in cytosol and plasma membrane |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer.
References
Zheng, S.L., et al. Prostate 70(4):425-432(2010)Hooker, S., et al. Prostate 70(3):270-275(2010)Huang, S.P., et al. Cancer Epidemiol. Biomarkers Prev. 18(11):3068-3074(2009)Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)Xu, J., et al. Cancer Epidemiol. Biomarkers Prev. 18(7):2145-2149(2009)Wiklund, F.E., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1659-1662(2009)
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