|Other Names||EH domain-binding protein 1, EHBP1, KIAA0903, NACSIN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in actin reorganization. Links clathrin- mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle trafficking (PubMed:14676205, PubMed:27552051). Required for perinuclear sorting and insulin-regulated recycling of SLC2A4/GLUT4 in adipocytes (By similarity).|
|Cellular Location||Cytoplasm. Membrane. Endosome. Note=Mostly found in cytosol and plasma membrane|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer.
Zheng, S.L., et al. Prostate 70(4):425-432(2010)Hooker, S., et al. Prostate 70(3):270-275(2010)Huang, S.P., et al. Cancer Epidemiol. Biomarkers Prev. 18(11):3068-3074(2009)Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)Xu, J., et al. Cancer Epidemiol. Biomarkers Prev. 18(7):2145-2149(2009)Wiklund, F.E., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1659-1662(2009)
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