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T4S4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P48230 |
|---|
| Gene ID | 7104 |
|---|---|
| Other Names | Transmembrane 4 L6 family member 4, Intestine and liver tetraspan membrane protein, IL-TMP, TM4SF4, ILTMP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TM4SF4 |
|---|---|
| Synonyms | ILTMP |
| Function | Regulates the adhesive and proliferative status of intestinal epithelial cells. Can mediate density-dependent cell proliferation. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Jejunum and liver. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation. The use of alternate polyadenylation sites has been found for this gene.
References
Qiao, J., et al. Reprod. Biomed. Online 17(3):425-435(2008)Berditchevski, F. J. Cell. Sci. 114 (PT 23), 4143-4151 (2001) Wright, M.D., et al. Protein Sci. 9(8):1594-1600(2000)
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