|Other Names||Rho GTPase-activating protein 19, Rho-type GTPase-activating protein 19, ARHGAP19|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.|
|Tissue Location||Strong expression in fetal heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Weak expression in adult pancreas, spleen, thymus, and ovary|
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Provided below are standard protocols that you may find useful for product applications.
Members of the ARHGAP family, such as ARHGAP19, encode negative regulators of Rho GTPases (see RHOA; MIM 165390), which are involved in cell migration, proliferation, and differentiation, actin remodeling, and G1 cell cycle progression.
Lv, L., et al. DNA Seq. 18(3):184-189(2007)Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Deloukas, P., et al. Nature 429(6990):375-381(2004)Jikuya, H., et al. DNA Res. 10(1):49-57(2003)
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