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STX1A Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16623
Peptide ID 90625223
Additional Information
Gene ID 6804
Other Names Syntaxin-1A, Neuron-specific antigen HPC-1, STX1A, STX1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name STX1A
Synonyms STX1
Function Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
Cellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome
Tissue Location Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.
Research Areas
Citations (0)

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This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.


Yoshida, T., et al. Int. J. Mol. Med. 24(2):233-246(2009)Hamdan, F.F., et al. Ann. Neurol. 65(6):748-753(2009)Corominas, R., et al. Neurosci. Lett. 455(2):105-109(2009)Chen, C.S., et al. J. Biol. Chem. 284(11):6877-6884(2009)Ramakrishnan, N.A., et al. J. Biol. Chem. 284(3):1364-1372(2009)Tian, J.H., et al. J. Biol. Chem. 278(28):26265-26274(2003)

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$ 80.00
Cat# BP9813a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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