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MBL2 Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P11226
Additional Information
Gene ID 4153
Other Names Mannose-binding protein C, MBP-C, Collectin-1, MBP1, Mannan-binding protein, Mannose-binding lectin, MBL2, COLEC1, MBL
Target/Specificity The synthetic peptide sequence is selected from aa 210-221 of HUMAN MBL2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MBL2
Synonyms COLEC1, MBL
Function Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Cellular Location Secreted.
Tissue Location Plasma protein produced mainly in the liver.
Research Areas
Citations (0)

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This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.


Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
Davila, S., et al. Genes Immun. (2010) In press :
Dahl, M. Clin Respir J 3(2):121-122(2009)
Garred, P., et al. Clin. Exp. Immunol. 90(3):517-521(1992)

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$ 80.00
$ 99.00
Cat# BP9821a
(40 western blots)
Availability: 2 weeks
Bulk Size
Seasonal Special on Bulk Order
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