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CLDN15 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P56746
Peptide ID 90909123
Additional Information
Gene ID 24146
Other Names Claudin-15, CLDN15
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLDN15
Function Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members function as impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN15 forms tight junctions that mediate the paracellular transport of small monovalent cations along a concentration gradient, due to selective permeability for Na(+), Li(+) and K(+) ions, but selects against Cl(-) ions. Plays an important role in paracellular Na(+) transport in the intestine and in Na(+) homeostasis. Required for normal Na(+)-dependent intestinal nutrient uptake.
Cellular Location Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=Tight junctions form continuous circumferential cell-cell contacts at the borders of apical and lateral cell membranes that seal the intercellular space and show up as strand-like structures in electron microscopy
Tissue Location Detected in colon (at protein level).
Research Areas
Citations (0)

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Plays a major role in tight junction specific obliteration of the intercellular space, through calcium independent cell adhesion activity


Van Itallie, C.M., et al. Am. J. Physiol. Renal Physiol. 285 (6), F1078-F1084 (2003) Gonzalez-Mariscal, L., et al. Prog. Biophys. Mol. Biol. 81(1):1-44(2003)Tsukita, S., et al. Curr. Opin. Cell Biol. 14(5):531-536(2002)Colegio, O.R., et al. Am. J. Physiol., Cell Physiol. 283 (1), C142-C147 (2002)

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$ 80.00
Cat# BP9831c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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