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SC16B Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96JE7 |
|---|
| Gene ID | 89866 |
|---|---|
| Other Names | Protein transport protein Sec16B, Leucine zipper transcription regulator 2, Regucalcin gene promoter region-related protein p117, RGPR-p117, SEC16 homolog B, SEC16B, KIAA1928, LZTR2, RGPR, SEC16S |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SEC16B |
|---|---|
| Synonyms | KIAA1928, LZTR2, RGPR, SEC16S |
| Function | Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:17192411, PubMed:21768384, PubMed:22355596). Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes (PubMed:21768384). |
| Cellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Note=Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
SEC16B is a mammalian homolog of S. cerevisiae Sec16 that is required for organization of transitional endoplasmic reticulum (ER) sites and protein export (Bhattacharyya and Glick, 2007.
References
Li, S., et al. Am. J. Clin. Nutr. 91(1):184-190(2010)Hotta, K., et al. J. Hum. Genet. 54(12):727-731(2009)Yamaguchi, M. Mol. Cell. Biochem. 327 (1-2), 53-63 (2009) Thorleifsson, G., et al. Nat. Genet. 41(1):18-24(2009)Bhattacharyya, D., et al. Mol. Biol. Cell 18(3):839-849(2007)
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