ETS2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P15036 |
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Gene ID | 2114 |
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Other Names | Protein C-ets-2, ETS2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ETS2 |
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Function | Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes.
References
Zabuawala, T., et al. Cancer Res. 70(4):1323-1333(2010)Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Shalaby, A.A., et al. Mod. Pathol. 22(8):996-1005(2009)Sutter, W., et al. J Craniomaxillofac Surg 37(5):263-271(2009)Staun-Ram, E., et al. Reprod. Biol. Endocrinol. 7, 135 (2009)
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