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CC28B Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BUN5 |
|---|
| Gene ID | 79140 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 28B, CCDC28B |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CCDC28B |
|---|---|
| Function | Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=It localizes near centrosomes and basal bodies |
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Provided below are standard protocols that you may find useful for product applications.
Background
The product of this gene localizes to centrosomes and basal bodies. It interacts and colocalizes with several proteins associated with Bardet-Biedl syndrome.
References
Bin, J., et al. Hum. Mutat. 30 (7), E737-E746 (2009) Badano, J.L., et al. Nature 439(7074):326-330(2006)
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