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CDC45L Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O75419
Peptide ID 90429067
Additional Information
Gene ID 8318
Other Names Cell division control protein 45 homolog, PORC-PI-1, CDC45, CDC45L, CDC45L2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC45
Synonyms CDC45L, CDC45L2
Function Required for initiation of chromosomal DNA replication.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Widely expressed, highest levels are found in adult testis and thymus and in fetal liver
Research Areas
Citations (0)

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The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported.


Chowdhury, A., et al. Mol. Cell. Biol. 30(6):1495-1507(2010)Im, J.S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(37):15628-15632(2009)Ballabeni, A., et al. J. Biol. Chem. 284(5):3028-3036(2009)Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008)Hoskins, J.M., et al. Clin. Cancer Res. 14(6):1788-1796(2008)

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$ 80.00
Cat# BP9881c
(40 western blots)
Availability: In Stock
Bulk Size
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