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RGR Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P47804
Peptide ID 91102324
Additional Information
Gene ID 5995
Other Names RPE-retinal G protein-coupled receptor, RGR
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGR
Function Receptor for all-trans- and 11-cis-retinal. Binds preferentially to the former and may catalyze the isomerization of the chromophore by a retinochrome-like mechanism.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cells of the neural retina
Research Areas
Citations (0)

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This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).


Kochounian, H., et al. Exp. Eye Res. 88(6):1129-1136(2009)Radu, R.A., et al. J. Biol. Chem. 283(28):19730-19738(2008)Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)Lin, M.Y., et al. Mol. Vis. 13, 1203-1214 (2007)

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$ 80.00
Cat# BP9895c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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