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IMP3 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NV31
Additional Information
Gene ID 55272
Other Names U3 small nucleolar ribonucleoprotein protein IMP3, U3 snoRNP protein IMP3, BRMS2, IMP3, C15orf12, MRPS4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IMP3 (HGNC:14497)
Synonyms C15orf12, MRPS4
Function Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
Cellular Location Nucleus, nucleolus
Research Areas
Citations (0)
citation

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Background

This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain.

References

Li, D., et al. Ann. Surg. Oncol. 16(12):3499-3506(2009)Walter, O., et al. Hum. Pathol. 40(11):1528-1533(2009)Riener, M.O., et al. Hum. Pathol. 40(10):1377-1383(2009)Noske, A., et al. Int. J. Gynecol. Pathol. 28(3):203-210(2009)

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$ 277.78
Cat# BP9901b
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