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C12orf11 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NVM9 |
|---|
| Gene ID | 55726 |
|---|---|
| Other Names | Protein asunder homolog, Cell cycle regulator Mat89Bb homolog, Germ cell tumor 1, Sarcoma antigen NY-SAR-95, ASUN, C12orf11, GCT1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | INTS13 (HGNC:20174) |
|---|---|
| Function | Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267). |
| Cellular Location | Nucleus. Cytoplasm Note=Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M. |
| Tissue Location | Widely expressed. Tends to be up-regulated in seminomas compared to normal testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)Lee, L.A., et al. Dev. Cell 8(3):435-442(2005)Lee, S.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 100(5):2651-2656(2003)Bourdon, V., et al. Cancer Res. 62(21):6218-6223(2002)
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