GBP6 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6ZN66 |
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Gene ID | 163351 |
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Other Names | Guanylate-binding protein 6, GTP-binding protein 6, GBP-6, Guanine nucleotide-binding protein 6, GBP6 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GBP6 |
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Function | Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens, such as bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii (By similarity). Confers protection to several pathogens, including the bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii (By similarity). |
Cellular Location | Cytoplasmic vesicle {ECO:0000250|UniProtKB:A0A0G2JDV3} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP.
References
Olszewski, M.A., et al. J. Interferon Cytokine Res. 26(5):328-352(2006)Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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