|Other Names||Cytosolic 5'-nucleotidase 1A, cN1A, Cytosolic 5'-nucleotidase IA, cN-I, cN-IA, NT5C1A|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.|
|Tissue Location||Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates.
Landers, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(22):9004-9009(2009)Lechward, K., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(4):280-284(2009)Fyrberg, A., et al. Nucleosides Nucleotides Nucleic Acids 25 (9-11), 1201-1204 (2006) :
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