|Other Names||Arylsulfatase I, ASI, 316-, ARSI|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts.|
|Cellular Location||Secreted. Endoplasmic reticulum Note=Localized in the intracellular granular structures|
|Tissue Location||Expressed in placenta, in embryonic stem cells, fetal eyes and lens.|
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Provided below are standard protocols that you may find useful for product applications.
Sulfatases (EC 22.214.171.124), such as ARSI, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules
Oshikawa, M., et al. Mol. Vis. 15, 482-494 (2009) Obaya, A.J. Gene 372, 110-117 (2006) Sardiello, M., et al. Hum. Mol. Genet. 14(21):3203-3217(2005)
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