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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CES1 Antibody (C-term) Blocking Peptide   

CES1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P23141
Peptide ID 35358
Additional Information
Gene ID 1066
Other Names Liver carboxylesterase 1, Acyl-coenzyme A:cholesterol acyltransferase, ACAT, Brain carboxylesterase hBr1, Carboxylesterase 1, CE-1, hCE-1, Cocaine carboxylesterase, Egasyn, HMSE, Methylumbelliferyl-acetate deacetylase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, REH, Serine esterase 1, Triacylglycerol hydrolase, TGH, CES1, CES2, SES1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CES1
Synonyms CES2, SES1
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.
Cellular Location Endoplasmic reticulum lumen
Tissue Location Expressed predominantly in liver with lower levels in heart and lung.
Research Areas
Citations (0)

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Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.


Maruichi, T., et al. Biochem. Pharmacol. 79(2):288-295(2010)Nemoda, Z., et al. Neuropharmacology 57 (7-8), 731-733 (2009) :Na, K., et al. Proteomics 9(16):3989-3999(2009)Sanghani, S.P., et al. Protein Pept. Lett. 16(10):1207-1214(2009)

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$ 80.00
Cat# BP9927b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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