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ATG13 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75143
Additional Information
Gene ID 9776
Other Names Autophagy-related protein 13, ATG13, KIAA0652
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATG13
Synonyms KIAA0652
Function Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Cellular Location Cytoplasm, cytosol. Preautophagosomal structure. Note=Under starvation conditions, is localized to puncate structures primarily representing the isolation membrane; the isolation membrane sequesters a portion of the cytoplasm resulting in autophagosome formation
Research Areas
Citations (0)
citation

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References

Hosokawa, N., et al. Autophagy 5(7):973-979(2009) Mercer, C.A., et al. Autophagy 5(5):649-662(2009) Ganley, I.G., et al. J. Biol. Chem. 284(18):12297-12305(2009) Jung, C.H., et al. Mol. Biol. Cell 20(7):1992-2003(2009) Hosokawa, N., et al. Mol. Biol. Cell 20(7):1981-1991(2009)

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$ 277.78
Cat# BP9928a
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