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SDR Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O95810
Peptide ID 27071
Additional Information
Gene ID 8436
Other Names Serum deprivation-response protein, Cavin-2, PS-p68, Phosphatidylserine-binding protein, SDPR {ECO:0000312|EMBL:AAD177951}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDPR {ECO:0000312|EMBL:AAD17795.1}
Function May play a role in targeting PRKCA to caveolae.
Cellular Location Cytoplasm, cytosol Membrane, caveola {ECO:0000250|UniProtKB:Q66H98}. Note=Colocalizes with CAV1 to caveolae. {ECO:0000250|UniProtKB:Q66H98}
Tissue Location Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.
Research Areas
Citations (0)

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Background

This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.

References

Baig, A., et al. Proteomics 9(17):4254-4258(2009)Hansen, C.G., et al. Nat. Cell Biol. 11(7):807-814(2009)Ogata, T., et al. Mol. Cell. Biol. 28(10):3424-3436(2008)

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$ 80.00
Cat# BP9935c
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