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ERC2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O15083
Peptide ID 91009021
Additional Information
Gene ID 26059
Other Names ERC protein 2, ERC2, KIAA0378
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ERC2
Synonyms KIAA0378
Function Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Cellular Location Cytoplasm. Cell junction, synapse. Cell junction, synapse, synaptosome Cytoplasm, cytoskeleton. Note=In neurons, localized to synapses, and colocalizes with PCLO Localized to the active zone of presynaptic density (By similarity).
Research Areas
Citations (0)

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ERCs (ERC1 and ERC2) also referred to as ELKS and CAST are related proteins which share an identical C-terminal sequence. They interact with the conserved RIM PDZ domain via an unusual PDZ binding motif. ERC2/CAST 1 is only expressed as a single RIM binding variant. All ERCs have been shown to interact with Rab6, a protein involved in membrane trafficking at the Golgi complex. The function of these proteins has not been determined yet. They may link Rab6 mediated non-neuronal membrane traffic at the Golgi complex to neuronal membrane traffic at the active zone executed via RIMs.


Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008)Kiel, D.P., et al. BMC Med. Genet. 8 SUPPL 1, S14 (2007) tom Dieck, S., et al. J. Cell Biol. 168(5):825-836(2005)

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$ 80.00
Cat# BP9944b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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