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CENPM Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NSP4
Peptide ID 35350
Additional Information
Gene ID 79019
Other Names Centromere protein M, CENP-M, Interphase centromere complex protein 39, Proliferation-associated nuclear element protein 1, CENPM, C22orf18, ICEN39, PANE1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C22orf18, ICEN39, PANE1
Function Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.
Cellular Location Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Nuclear in non-confluent cells and cytoplasmic in confluent or dividing cells (By similarity). Localizes in the kinetochore domain of centromeres.
Tissue Location Isoform 3 is highly expressed in spleen, and intermediately in heart, prostate and ovary. Isoform 3 is highly expressed in resting CD19 B-cells and B-lineage chronic lymphocytic leukemia (B-CLL) cells and weakly expressed in activated B-cells. Isoform 1 is selectively expressed in activated CD19 cells and weakly in resting CD19 B-cells
Research Areas
Citations (0)

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CENPMe is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly.


Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Izuta, H., et al. Genes Cells 11(6):673-684(2006)Brickner, A.G., et al. Blood 107(9):3779-3786(2006)Okada, M., et al. Nat. Cell Biol. 8(5):446-457(2006)

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$ 80.00
Cat# BP9955a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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