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ID4 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P47928
Peptide ID 91013150
Additional Information
Gene ID 3400
Other Names DNA-binding protein inhibitor ID-4, Class B basic helix-loop-helix protein 27, bHLHb27, Inhibitor of DNA binding 4, Inhibitor of differentiation 4, ID4, BHLHB27
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ID4
Synonyms BHLHB27
Function Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)

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ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins


Fontemaggi, G., et al. Nat. Struct. Mol. Biol. 16(10):1086-1093(2009)Uhm, K.O., et al. J. Korean Med. Sci. 24(3):493-497(2009)

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$ 80.00
Cat# BP9977a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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