ZNF268 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q14587 |
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Gene ID | 10795 |
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Other Names | Zinc finger protein 268, Zinc finger protein HZF3, ZNF268 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ZNF268 |
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Function | [Isoform 1]: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression. |
Cellular Location | [Isoform 1]: Nucleus |
Tissue Location | Overexpressed in ovarian cancer tissues compared to normal ovarian tissues. Isoform 1 and isoform 2 are expressed in squamous epithelium tissues. Isoform 2 is overexpressed in squamous cervical cancer (at protein level). Expressed in blood cells. Isoform 1 is expressed in pancreas, lung, skeletal muscle, heart, placenta, liver, kidney and brain. Isoform 2 expressed in chronic lymphocytic leukemia (CLL) and several tumor cell lines. Isoform 3 is expressed in several tumor cells. Isoform 5 is expressed in fetal liver and several tumor cells. Isoform 6 is weakly expressed in brain, lung amd small intestin and in several tumor cells. Isoform 7 is expressed in fetal liver and several tumor cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF268 may be involved in transcriptional regulation.
References
Zhao, Z., et al. Oncol. Rep. 20(5):1243-1248(2008)Chun, J.N., et al. Mol. Cells 26(2):175-180(2008)Zhu, C., et al. Biochemistry Mosc. 73(8):881-885(2008)
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