UTP15 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8TED0 |
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Gene ID | 84135 |
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Other Names | U3 small nucleolar RNA-associated protein 15 homolog, UTP15 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | UTP15 (HGNC:25758) |
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Function | Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I (PubMed:17699751). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). |
Cellular Location | Nucleus, nucleolus. Note=Found predominantly at the fibrillar center. |
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Provided below are standard protocols that you may find useful for product applications.
Background
UTP15 involved in nucleolar processing of pre-18S ribosomal RNA.
References
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
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