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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NAL11 Antibody (Center) Blocking Peptide   

NAL11 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P59045
Peptide ID 91109105
Additional Information
Gene ID 204801
Other Names NACHT, LRR and PYD domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17, PAAD-and NACHT domain-containing protein 10, PYRIN-containing APAF1-like protein 6, NLRP11, NALP11, NOD17, PAN10, PYPAF6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NLRP11
Synonyms NALP11, NOD17, PAN10, PYPAF6
Function Involved in inflammation.
Research Areas
Citations (0)

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Background

NAL11 are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NAL11 are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes.

References

Baranzini, S.E., et al. Hum. Mol. Genet. 18(4):767-778(2009)Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008)Dowds, T.A., et al. Biochem. Biophys. Res. Commun. 302(3):575-580(2003)

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$ 80.00
Cat# BP9991a
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