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MAPK12 Over-expression LysateGene specific transient over-expression cell lysates
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| LY10151a | 100ug 400 ul | 3-4 weeks | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
MAPK12 Over-expression Lysate - Product info | |
| Application | WB
|
| Other Accession | NM_002969.3 |
MAPK12 Over-expression Lysate - Additional info | |
| Gene Symbol | MAPK12 |
| Other Names ERK3, ERK6, P38GAMMA, PRKM12, SAPK-3, SAPK3 | |
| Format over-expression cell lysate in RIPA buffer | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
MAPK12 Over-expression Lysate - Related products
AP7224c: MAPK12 Antibody (Center)
AP7511a: MAPK12 Antibody (C-term)
RI13186: MAPK12 predesign siRNA
MAPK12 Over-expression Lysate - Application data
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Western blot analysis of his-tag MAPK12 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MAPK12 gene (Lane 2, Cat. #LY10151a).
MAPK12 Over-expression Lysate - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
REFERENCES
PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction. Hou SW, et al. Cancer Res, 2010 Apr 1. PMID 20332238. p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms. Kwong J, et al. J Biol Chem, 2009 Apr 24. PMID 19251701. Implication of p38 mitogen-activated protein kinase isoforms (alpha, beta, gamma and delta) in CD4+ T-cell infection with human immunodeficiency virus type I. Gutierrez-Sanmartin D, et al. J Gen Virol, 2008 Jul. PMID 18559936. p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response. Qi X, et al. J Biol Chem, 2007 Oct 26. PMID 17724032. Hyperactive variants of p38alpha induce, whereas hyperactive variants of p38gamma suppress, activating protein 1-mediated transcription. Askari N, et al. J Biol Chem, 2007 Jan 5. PMID 17088247.
