- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
MAP2K1 Over-expression LysateGene specific transient over-expression cell lysates
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| LY10623a | 100ug 400 ul | 3-4 weeks | $ 325.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
MAP2K1 Over-expression Lysate - Product info | |
| Application | WB
|
| Other Accession | NM_002755.3 |
MAP2K1 Over-expression Lysate - Additional info | |
| Gene Symbol | MAP2K1 |
| Other Names MAPKK1, MEK1, MKK1, PRKMK1 | |
| Format over-expression cell lysate in RIPA buffer | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
MAP2K1 Over-expression Lysate - Related products
AP3158a: Phospho-MEK1/2-S218/222 Antibody
AP3159a: Phospho-MEK1-S218/222 Antibody
AP3317a: Phospho-MAP2K1-S217 Antibody
AP3318a: Phospho-MAP2K1-T291 Antibody
AP3319a: Phospho-MAP2K1-S297 Antibody
AP3320a: Phospho-MAP2K1-T385 Antibody
AP3611a: Phospho-MEK1-pS218 Antibody
AP3612a: Phospho-MEK1-pS222 Antibody
AP7904b: MAP2K1(S218)/MAP2K2 (S216) Antibody
AP7960a: MEK1 (MAP2K1) Antibody (N-term)
AP7960c: MEK1 Antibody (Center)
AP7960d: MEK1 (MAP2K1) Antibody (S218)
AP7960e: MAP2K1 Antibody (T291)
AP7960f: MAP2K1 Antibody (S297)
AP7960g: MAP2K1 Antibody (T385)
AP7960h: MEK1 Antibody (S218/222)
AP7960i: MAP2K1 Antibody (T285)
AP7960j: MAP2K1 Antibody ( S221 )
RI13154: MAP2K1 predesign siRNA
MAP2K1 Over-expression Lysate - Application data
-
Western blot analysis of his-tag MAP2K1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MAP2K1 gene (Lane 2, Cat. #LY10623a).
MAP2K1 Over-expression Lysate - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
REFERENCES
MEK1 and AKT2 mutations in Japanese lung cancer. Sasaki H, et al. J Thorac Oncol, 2010 May. PMID 20354455. Investigation of gene dosage imbalances in patients with Noonan syndrome using multiplex ligation-dependent probe amplification analysis. Nystr?m AM, et al. Eur J Med Genet, 2010 May-Jun. PMID 20302979. MicroRNA-34a inhibits cell proliferation by repressing mitogen-activated protein kinase kinase 1 during megakaryocytic differentiation of K562 cells. Ichimura A, et al. Mol Pharmacol, 2010 Jun. PMID 20299489. The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1. Khanal P, et al. Mol Cancer Ther, 2010 Mar. PMID 20179161. Distinct effects of knocking down MEK1 and MEK2 on replication of herpes simplex virus type 2. Zhang H, et al. Virus Res, 2010 Jun. PMID 20172001.
