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Recombinant Rat FGF-basic
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Description | FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant rat FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues. |
|---|---|
| BiologicalActivity | The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells is ≤ 0.2 ng/ml corresponding to a specific activity of ≥5 x 106 units/mg. |
| Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
| Endotoxin | Endotoxin level is <0.1 ng/ µg of protein (<1EU/ µg). |
| Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
| Storage | -20°C |
| Precautions | Recombinant Rat FGF-basic is for research use only and not for use in diagnostic or therapeutic procedures. |
Citations (0)
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$ 216.00
$ 96.00
Cat# PBG10109-U050
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