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Recombinant Human IL-33

     
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Description Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.
BiologicalActivity The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.
Authenticity Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin Endotoxin level is <0.1 ng/ µg of protein (<1EU/ µg).
Protein Content Verified by UV Spectroscopy and/or SDS-PAGE gel.
Storage-20°C
PrecautionsRecombinant Human IL-33 is for research use only and not for use in diagnostic or therapeutic procedures.
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$ 216.00
$ 96.00
Cat# PBG10228-U010
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