Recombinant Human I-TAC (CXCL11)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Description | I-TAC is a 'non-ELR' CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, or monocytes. Recombinant human I-TAC is an 8.3 kDa protein containing 73 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines. |
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BiologicalActivity | Determined by its ability to chemoattract IL-2 activated T-cells using a concentration range of 0.1-10.0 ng/ml. |
Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
Endotoxin | Endotoxin level is <0.1 ng/ µg of protein (<1EU/ µg). |
Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
Storage | -20°C |
Precautions | Recombinant Human I-TAC (CXCL11) is for research use only and not for use in diagnostic or therapeutic procedures. |
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