Recombinant Human LAG-1 (CCL4L1)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Description | LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues. |
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BiologicalActivity | Determined by it's ability to chemoattract CCR5 transfected cells using a concentration of 0.1-10.0 ng/ml |
Authenticity | Verified by N-terminal and Mass Spectrometry analyses (when applicable). |
Endotoxin | Endotoxin level is <0.1 ng/ µg of protein (<1EU/ µg). |
Protein Content | Verified by UV Spectroscopy and/or SDS-PAGE gel. |
Storage | -20°C |
Precautions | Recombinant Human LAG-1 (CCL4L1) is for research use only and not for use in diagnostic or therapeutic procedures. |
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