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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Caspase-1 Blocking Peptide   

Caspase-1 Blocking Peptide

Product Information
Primary Accession P29466
Other Accession NP_150636
Gene ID 834
Calculated MW 45159 Da
Additional Information
Gene ID 834
Application & Usage The peptide is used for blocking the antibody activity of active Caspase-1. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C
Other Names Caspase-1, CASP-1,, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p20, Caspase-1 subunit p10, CASP1, IL1BC, IL1BCE
Target/Specificity Caspase-1
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCaspase-1 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASP1
Synonyms IL1BC, IL1BCE
Function Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Cellular Location Cytoplasm.
Tissue Location Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.
Research Areas
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$ 95.00
Cat# PBV10005b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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