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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Bcl-2 Blocking Peptide   

Bcl-2 Blocking Peptide

Product Information
Primary Accession P10415
Other Accession M13994
Gene ID 596
Calculated MW 26266 Da
Additional Information
Gene ID 596
Application & Usage The peptide is used for blocking the antibody activity of active Bcl-2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C
Other Names Apoptosis regulator Bcl-2, BCL2
Target/Specificity Bcl-2
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsBcl-2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL2
Function Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Cellular Location Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Expressed in a variety of tissues.
Research Areas
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$ 95.00
Cat# PBV10014b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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