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Caspase-10/b, human recombinant protein


Product info
Calculated MW two large (18 kDa) and two small (11 kDa) subunits in a heterotetramer form.
Additional Info
Other Names Caspase-10, CASP-10, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4
Gene Source Human
Source E.coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC;
Recombinant Yes
Target/Specificity Caspase-10/b
Application Notes Reconstitute to 1 unit per µl in PBS containing 15% glycerol.
Format Lyophilized powder
Storage -70°C; Lyophilized powder
Citations (0)

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Caspase-10b (also known as FLICE 2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-10 also exists in cells as an inactive proenzyme. During apoptosis procaspase-10 is processed at aspartate residues to form active caspase-10 which consists of two large (18 kDa) and two small (11 kDa) subunits in a heterotetramer form. The recombinant active human caspase-10/b was expressed in E. coli. The active caspase-10 is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-IETD-pNA or Ac-IETD-AFC

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$ 305.00
$ 175.00
Cat# PBV10021r
(40 western blots)
Availability: 5-7days
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