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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PRMT7 blocking peptide   

PRMT7 blocking peptide

Product Information
Primary Accession Q9NVM4
Gene ID 54496
Calculated MW 78459 Da
Additional Information
Gene ID 54496
Application & Usage The peptide is used for blocking the antibody activity of PRMT7. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Protein arginine N-methyltransferase 7, 2.1.1.-, Histone-arginine N-methyltransferase PRMT7,, [Myelin basic protein]-arginine N-methyltransferase PRMT7,, PRMT7, KIAA1933
Target/Specificity PRMT7
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPRMT7 blocking peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRMT7
Synonyms KIAA1933
Function Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
Cellular Location Cytoplasm, cytosol. Nucleus
Research Areas
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$ 95.00
Cat# PBV10024b
(40 western blots)
Availability: 5-7days
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